Dermatologic adverse events from cancer treatments Book Section


Authors: Wu, J.; Markova, A.; Lacouture, M. E.
Editors: Shear, N. H.; Dodiuk-Gad, R. P.
Article/Chapter Title: Dermatologic adverse events from cancer treatments
Abstract: The incidences of adverse events to cancer treatments have increased as new treatments are being developed. Dermatologic adverse events (dAEs) strongly impact patients’ quality of life (QoL). Severe dAEs can result in dose reduction or discontinuation, which may compromise clinical outcomes and even lead to life-threatening conditions. Prevention, early diagnosis, and proper management of dAEs are crucial for optimizing anticancer response and maintaining QoL. This chapter addresses dAEs induced by cytotoxic and targeted therapies, radiotherapy, stem cell transplantation, immunotherapies, and CAR-T cell therapy. Proposed underling mechanisms and recommended treatment approaches for these dAEs are presented. © Springer Nature Singapore Pte Ltd. 2019.
Keywords: skin toxicity; chemotherapy; immunotherapy; targeted therapy; checkpoint inhibitor; dermatologic adverse event (dae); immune-related adverse event (irae)
Book Title: Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions: Current and Future Trends
ISBN: 978-981-13-1488-9
Publisher: Springer Singapore  
Publication Place: Singapore
Date Published: 2019-01-01
Start Page: 131
End Page: 173
Language: English
DOI: 10.1007/978-981-13-1489-6_10
PROVIDER: scopus
DOI/URL:
Notes: Book chapter: 10 -- This chapter is located under "Part III Clinical Perspectives of Cutaneous Adverse Drug Reactions" -- Source: Scopus
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  1. Mario E Lacouture
    457 Lacouture
  2. Alina Markova
    87 Markova
  3. Jennifer Wu
    8 Wu