Author: | Wuest, D. L. |
Article Title: | Transfusion and stem cell support in cancer treatment |
Abstract: | Intensification of therapeutic regimens, improved patient survival, and advances in cytokine and cellular therapies have led to increasingly complex requirements for transfusion and stem cell support in cancer treatment. This article focuses on current and evolving issues in red blood cell, platelet, and granulocyte transfusion support, as well as measures to avoid increasingly important complications of transfusion therapy, such as alloimmunization, graft-versus-host disease, cytomegalovirus infection, and immunomodulation. Issues concerning current applications of hematopoietic stem cell transplantation and future prospects also are discussed. |
Keywords: | clinical feature; clinical trial; review; medical decision making; anemia; thrombocytopenia; clinical protocol; stem cell transplantation; risk factor; hla matching; neutrophil; prophylaxis; graft versus host reaction; gamma irradiation; hematopoietic stem cell; erythrocyte transfusion; cytomegalovirus infection; virus transmission; thrombocyte transfusion; bleeding tendency; alloimmunity; leukocyte transfusion; cancer; human; priority journal |
Journal Title: | Hematology/Oncology Clinics of North America |
Volume: | 10 |
Issue: | 2 |
ISSN: | 0889-8588 |
Publisher: | Elsevier Inc. |
Date Published: | 1996-04-01 |
Start Page: | 397 |
End Page: | 429 |
Language: | English |
DOI: | 10.1016/s0889-8588(05)70345-2 |
PUBMED: | 8707762 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Export Date: 22 November 2017 -- Source: Scopus |