Adjuvant analgesic agents Journal Article
| Author: | Portenoy, R. K. |
| Article Title: | Adjuvant analgesic agents |
| Abstract: | Adjuvant analgesics are usually considered when the patient with cancer pain fails to attain a satisfactory balance between analgesia and side effects during opioid therapy, or experiences a comorbid symptom or disorder that may be amenable to one of the adjuvant drugs. When pain is the primary indication, the use of adjuvant analgesics is one strategy that must be evaluated in comparison with other potentially analgesic approaches. The potential costs, inconvenience, and risks associated with polypharmacy must be balanced by demonstrable benefits. To offer the most informed recommendation, the clinician must have a strong working knowledge of the many drugs currently used as adjuvant analgesics and a detailed assessment of the patient and pain syndrome. |
| Keywords: | review; dose response; cancer adjuvant therapy; unindexed drug; bone marrow suppression; neuropathy; calcitonin; bone pain; cancer pain; gastrointestinal toxicity; hypotension; insomnia; depression; narcotic analgesic agent; nonsteroid antiinflammatory agent; benzodiazepine derivative; neuroleptic agent; cognitive defect; octreotide; intestine obstruction; somnolence; lidocaine; anticonvulsive agent; corticosteroid; analgesia; clonazepam; intravenous drug administration; mexiletine; carbamazepine; gabapentin; local anesthetic agent; oral drug administration; tricyclic antidepressant agent; capsaicin; vertigo; pamidronic acid; dysesthesia; clonidine; amitriptyline; strontium 89; scopolamine bromide; propranolol; glycopyrronium bromide; topical drug administration; gallium nitrate; baclofen; prazosin; human; priority journal; dextromethorphan; transdermal drug administration; felbamate |
| Journal Title: | Hematology/Oncology Clinics of North America |
| Volume: | 10 |
| Issue: | 1 |
| ISSN: | 0889-8588 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1996-02-01 |
| Start Page: | 103 |
| End Page: | 119 |
| Language: | English |
| DOI: | 10.1016/s0889-8588(05)70329-4 |
| PUBMED: | 8821562 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 22 November 2017 -- Source: Scopus |
