Signal transduction through lipid second messengers Journal Article
| Authors: | Spiegel, S.; Foster, D.; Kolesnick, R. |
| Article Title: | Signal transduction through lipid second messengers |
| Abstract: | This review emphasizes the generation of glycerolipid and sphingolipid second messengers, and their molecular targets. The role of the phosphatidylinositol transfer protein and phospholipase D in signal transmission, and the structures of the 1,2-diacylglycerol and calcium-binding sites of protein kinase C are discussed. Further, ceramide signaling through protein kinases and the role of cross-talk in the signaling of apoptosis and inflammation are addressed. |
| Keywords: | signal transduction; carrier protein; review; apoptosis; lipid; inflammation; protein kinase c; calcium binding protein; diacylglycerol; ceramide; enzyme conformation; second messenger; lipid transport; sphingolipid; phosphatidylinositol; phospholipase d; priority journal; glycerolipid |
| Journal Title: | Current Opinion in Cell Biology |
| Volume: | 8 |
| Issue: | 2 |
| ISSN: | 0955-0674 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1996-04-01 |
| Start Page: | 159 |
| End Page: | 167 |
| Language: | English |
| DOI: | 10.1016/s0955-0674(96)80061-5 |
| PUBMED: | 8791422 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 22 November 2017 -- Source: Scopus |
