Treatment of Burkitt's lymphoma in HIV-positive patients Journal Article
| Author: | Straus, D. J. |
| Article Title: | Treatment of Burkitt's lymphoma in HIV-positive patients |
| Abstract: | Many Burkitt's-type non-Hodgkin lymphomas (NHL) in patients without HIV infection are curable with current brief high-dose combination chemotherapy regimens. Burkitt's-type lymphomas (BL) comprise 30-40% of HIV-associated NHL. Their morphologic, clinical, cytogenetic and molecular genetic characteristics are similar to those of sporadic BL unassociated with HIV infection. They often occur in less immunosuppressed HIV-infected individuals than the other types of NHL. Most patients with HIV-associated NHL benefit as much from low-dose as from standard or high-dose chemotherapy with less toxicity. However, there may be a subpopulation of HIV-infected patients with Burkitt's-type NHL and well preserved immune status who may benefit from high-dose chemotherapy programs that are effective for BL patients without HIV infection. |
| Keywords: | cancer chemotherapy; prednisone; review; doxorubicin; treatment; cytarabine; methotrexate; human immunodeficiency virus infection; molecular genetics; etoposide; granulocyte macrophage colony stimulating factor; cyclophosphamide; dexamethasone; vincristine; ifosfamide; nonhodgkin lymphoma; asparaginase; bleomycin; mesna; burkitt lymphoma; hiv; human; priority journal; burkitt's lymphoma |
| Journal Title: | Biomedicine and Pharmacotherapy |
| Volume: | 50 |
| Issue: | 9 |
| ISSN: | 0753-3322 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1996-01-01 |
| Start Page: | 447 |
| End Page: | 450 |
| Language: | English |
| DOI: | 10.1016/s0753-3322(97)86004-0 |
| PUBMED: | 8991116 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 22 November 2017 -- Source: Scopus |
