Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE): Proposed miTNM classification for the interpretation of PSMA-ligand PET/CT Journal Article


Authors: Eiber, M.; Herrmann, K.; Calais, J.; Hadaschik, B.; Giesel, F. L.; Hartenbach, M.; Hope, T.; Reiter, R.; Maurer, T.; Weber, W. A.; Fendler, W. P.
Article Title: Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE): Proposed miTNM classification for the interpretation of PSMA-ligand PET/CT
Abstract: Prostate-specific membrane antigen (PSMA)-ligand PET imaging provides unprecedented accuracy for whole-body staging of prostate cancer. As PSMA-ligand PET/CT is increasingly adopted in clinical trials and routine practice worldwide, a unified language for image reporting is urgently needed. We propose a molecular imaging TNM system (miTNM, version 1.0) as a standardized reporting framework for PSMA-ligand PET/CT or PET/MRI. miTNM is designed to organize findings in comprehensible categories to promote the exchange of information among physicians and institutions. Additionally, flowcharts integrating findings of PSMA-ligand PET and morphologic imaging have been designed to guide image interpretation. Specific applications, such as assessment of prognosis or impact on management, should be evaluated in future trials. miTNM is a living framework that evolves with clinical experience and scientific data. © 2018 by the Society of Nuclear Medicine and Molecular Imaging.
Keywords: criteria; interpretation; promise; mitnm; psma-ligand pet/ct; standardized evaluation
Journal Title: Journal of Nuclear Medicine
Volume: 59
Issue: 3
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2018-03-01
Start Page: 469
End Page: 478
Language: English
DOI: 10.2967/jnumed.117.198119
PROVIDER: scopus
PUBMED: 29123012
DOI/URL:
Notes: Article -- Export Date: 1 May 2018 -- Source: Scopus
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  1. Wolfgang Andreas Weber
    173 Weber