De-escalating and escalating surgery in the management of early breast cancer Conference Paper


Author: Morrow, M.
Title: De-escalating and escalating surgery in the management of early breast cancer
Conference Title: 15th St. Gallen International Breast Cancer Conference
Abstract: In the setting of increased awareness regarding the need to address potential overtreatment in the management of breast cancer patients with favorable-prognosis disease, this article reviews three relevant instances in which the extent of surgery has been safely decreased: margin width in patients with ductal carcinoma in situ; axillary management in clinically node-negative women undergoing primary breast-conserving surgery; and the use of neoadjuvant chemotherapy followed by sentinel node biopsy for patients presenting with node-positive breast cancer. The management of the axillary nodes over the past decade highlights the potential to de-escalate surgery in the era of multimodality therapy. Similar opportunities exist for the use of radiotherapy. To fully realize the potential of de-escalating surgery, new communication strategies must be developed to convince patients that bigger is not necessarily better. © 2017 Elsevier Ltd
Keywords: breast cancer; neoadjuvant chemotherapy; margins; re-excision; axillary lymph node dissection; dcis; overtreatment
Journal Title Breast
Volume: 34
Issue: Suppl. 1
Conference Dates: 2017 Mar 15-18
Conference Location: Vienna, Austria
ISBN: 0960-9776
Publisher: Elsevier Inc.  
Date Published: 2017-08-01
Start Page: S1
End Page: S4
Language: English
DOI: 10.1016/j.breast.2017.06.018
PROVIDER: scopus
PUBMED: 28673537
DOI/URL:
Notes: Article -- Export Date: 2 April 2018 -- Source: Scopus
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  1. Monica Morrow
    772 Morrow