A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies Journal Article


Authors: Casey, E.; Bournazos, S.; Mo, G.; Mondello, P.; Tan, K. S.; Ravetch, J. V.; Scheinberg, D. A.
Article Title: A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies
Keywords: cancer chemotherapy; cancer survival; protein expression; unclassified drug; drug efficacy; nonhuman; rituximab; binding affinity; letter; protein domain; antineoplastic activity; prediction; cancer inhibition; immune response; antibody response; lymphoma; fc receptor; drug cytotoxicity; antigen binding; lymphocyte subpopulation; human versus animal comparison; human; priority journal; obinutuzumab; antineoplastic monoclonal antibody; fc receptor gamma
Journal Title: Leukemia
Volume: 32
Issue: 2
ISSN: 0887-6924
Publisher: Nature Publishing Group  
Date Published: 2018-02-01
Start Page: 547
End Page: 549
Language: English
DOI: 10.1038/leu.2017.293
PROVIDER: scopus
PMCID: PMC5803448
PUBMED: 28924242
DOI/URL:
Notes: Letter -- Export Date: 2 April 2018 -- Source: Scopus
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MSK Authors
  1. Emily Catherine Casey
    9 Casey
  2. Kay See   Tan
    241 Tan
  3. George   Mo
    4 Mo
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