Opportunities and challenges: Human papillomavirus and cancer Journal Article
| Authors: | Chu, C. S.; Pfister, D. G. |
| Article Title: | Opportunities and challenges: Human papillomavirus and cancer |
| Abstract: | Mucosal exposure to human papillomavirus (HPV) can lead to anogenital and head and neck (H&N) cancer. Vaccination at a young age can be almost 100% effective in preventing HPV infection with the viral subtypes in both men and women, at least for disease in the anogenital tract. Therapeutic strategies targeting HPV in cervical dysplasia and cancer are showing promise as well in regressing dysplasia and controlling disease. That HPV-positive H&N cancer is a different disease from HPV-negative disease, with different molecular and clinical features and prognosis, is becoming better appreciated. At this time, however, the NCCN Guidelines for H&N Cancers do not distinguish between the types. This is expected to change. Copyright © 2017 by the National Comprehensive Cancer Network. |
| Keywords: | virology; head and neck neoplasms; vaccination; uterine cervical neoplasms; uterine cervix tumor; head and neck tumor; papillomavirus infections; sexually transmitted disease; papillomavirus infection; humans; prognosis; human; male; female; sexually transmitted diseases, viral |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 15 |
| Issue: | 5.5 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2017-05-01 |
| Start Page: | 726 |
| End Page: | 729 |
| Language: | English |
| PUBMED: | 28515256 |
| PROVIDER: | scopus |
| DOI: | 10.6004/jnccn.2017.0085 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 2 April 2018 -- Source: Scopus |
