Antisense modulation of RNA processing as a therapeutic approach in cancer therapy Journal Article

   


Authors: Spraggon, L.; Cartegni, L.
Article Title: Antisense modulation of RNA processing as a therapeutic approach in cancer therapy
Abstract: Next-generation antisense technologies are re-emerging as viable and powerful approaches to the treatment of several genetic diseases. Similar strategies are also being applied to cancer therapy. Reprogramming of the expression of endogenous oncogenic products to replace them with functional antagonists, by interfering with alternative splicing (AS) or polyadenylation, provides a promising novel approach to address acquired drug resistance and previously undruggable targets. © 2013 Elsevier Ltd.
Journal Title: Drug Discovery Today: Therapeutic Strategies
Volume: 10
Issue: 3
ISSN: 1740-6773
Publisher: Elsevier Inc.  
Date Published: 2013-09-01
Start Page: e139
End Page: e148
Language: English
DOI: 10.1016/j.ddstr.2013.06.002
PROVIDER: scopus
PMCID: PMC4290377
PUBMED: 25589899
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84883252529&doi=10.1016%2fj.ddstr.2013.06.002&partnerID=40&md5=22d6e7705b4a3d24cbd12cc3fcee6d5a
Notes: Article -- Export Date: 6 February 2018 -- Source: Scopus
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MSK Authors
  1. Lee Spraggon
    16 Spraggon
  2. Luca Cartegni
    18 Cartegni
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