Chimeric antigen receptor (CAR) T and other T cell strategies for pancreas adenocarcinoma Journal Article
| Author: | Varghese, A. M. |
| Article Title: | Chimeric antigen receptor (CAR) T and other T cell strategies for pancreas adenocarcinoma |
| Abstract: | Treatments in metastatic pancreas cancer remain based in cytotoxic chemotherapy, and novel treatment strategies are needed. Building on the emerging role of T cell therapy in hematologic malignancies and our understanding of the underlying biology of pancreas cancer, research is growing in the role of T cell therapy for patients with solid tumors in general and more specifically patients with pancreas cancer. This review will focus on describing the biology of T cell therapy and its current applications in pancreas cancer. © Chinese Clinical Oncology. |
| Keywords: | unclassified drug; review; nonhuman; cancer patient; pancreas cancer; t lymphocyte; carcinoembryonic antigen; hematologic malignancy; immunotherapy; pancreas adenocarcinoma; chimeric antigen receptor; adoptive transfer; immunomodulation; mucin 1; immunosuppressive treatment; cd24 antigen; prostate stem cell antigen; cd19 antigen; mesothelin; mucin; tumor microenvironment; mucin 16; human; solid malignant neoplasm; chimeric antigen receptor (car) t cells |
| Journal Title: | Chinese Clinical Oncology |
| Volume: | 6 |
| Issue: | 6 |
| ISSN: | 2304-3865 |
| Publisher: | AME Publishing Company |
| Date Published: | 2017-11-01 |
| Start Page: | 66 |
| Language: | English |
| DOI: | 10.21037/cco.2017.09.04 |
| PROVIDER: | scopus |
| PUBMED: | 29156888 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 February 2018 -- Source: Scopus |
