Current concepts in cervical pathology Journal Article


Authors: Park, K. J.; Soslow, R. A.
Article Title: Current concepts in cervical pathology
Abstract: Context-The correct diagnosis and reporting of cervical in situ and invasive carcinoma are essential for the appropriate clinical management of patients with human papilloma- virus-associated disease.Objectives-To review common mistakes made in the diagnosis of cervical dysplasia and invasive carcinoma, describe variants and benign mimics of high-grade squamous intraepithelial lesion and adenocarcinoma in situ, and discuss available ancillary studies that can be useful in making the distinctions as well as to review important factors re-lated to prognosis that should be included in the pathology report.Data Sources-Review of current literature.Conclusions-There are many mimics and variants of cervical squamous and glandular lesions that can be resolved with ancillary studies and careful histologic examination. Prognostically important features, such as tumor size, presence of vascular invasion, and margin status, should always be included in the pathology report.
Keywords: review; cancer staging; neoplasm staging; adenocarcinoma; cytology; metabolism; diagnosis, differential; differential diagnosis; tumor markers, biological; tumor marker; histology; virology; cancer invasion; carcinoma in situ; genomics; invasive carcinoma; neoplasm invasiveness; virus infection; uterine cervical neoplasms; uterine cervix tumor; uterine cervix carcinoma; uterine cervix dysplasia; wart virus; uterine cervix carcinoma in situ; vagina smear; cervical intraepithelial neoplasia; papillomavirus infections; uterine cervical dysplasia; vaginal smears
Journal Title: Archives of Pathology & Laboratory Medicine
Volume: 133
Issue: 5
ISSN: 0003-9985
Publisher: College of American Pathologists  
Date Published: 2009-05-01
Start Page: 729
End Page: 738
Language: English
PUBMED: 19415947
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 8" - "Export Date: 30 November 2010" - "CODEN: ARPAA" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Kay Jung Park
    305 Park
  2. Robert Soslow
    793 Soslow