Non-Hodgkin lymphoma: Contribution of chest CT in the initial staging evaluation Journal Article


Authors: Castellino, R. A.; Hilton, S.; O'Brien, J. P.; Portlock, C. S.
Article Title: Non-Hodgkin lymphoma: Contribution of chest CT in the initial staging evaluation
Abstract: PURPOSE: To analyze incremental information derived from routinely obtained chest computed tomographic (CT) scans compared with chest radiographs in newly diagnosed non-Hodgkin lymphoma and the effect of this information on staging and therapy. MATERIALS AND METHODS: Abnormalities on chest radiographs and CT scans obtained at specific sites were prospectively identified in 181 consecutive patients with no previous treatment. When discrepant information was found, the effect on staging and treatment was determined. RESULTS: CT and chest radiographic findings were negative in 99 (55%) patients. CT findings were positive and chest radiograph findings were negative in 17 (9%). Both chest radiograph and CT findings were positive in 65 (36%) patients, 16 with identical sites of disease and 49 with more extensive intrathoracic disease at CT. Most stage changes occurred in the diffuse large cell histologic subtype. CONCLUSION: Although routine chest CT findings increased stage of disease in some patients, it had no effect on initial treatment of newly diagnosed non-Hodgkin lymphoma at this institution.
Keywords: adolescent; adult; treatment outcome; aged; middle aged; major clinical study; clinical trial; histopathology; treatment planning; cancer staging; neoplasm staging; cancer grading; image analysis; prevalence; tomography, x-ray computed; thoracic neoplasms; nonhodgkin lymphoma; lymphoma, non-hodgkin; thorax radiography; humans; human; male; female; priority journal; article; thorax, ct; lymphoma, ct; lymphoma, staging; thorax, neoplasms
Journal Title: Radiology
Volume: 199
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1996-04-01
Start Page: 129
End Page: 132
Language: English
PUBMED: 8633134
PROVIDER: scopus
DOI: 10.1148/radiology.199.1.8633134
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
Altmetric Score
MSK Authors
  1. Carol Portlock
    188 Portlock
  2. James O'Brien
    20 O'Brien
  3. Susan Hilton
    28 Hilton