Pseudoangiomatous stromal hyperplasia: Mammographic, sonographic, and clinical patterns Journal Article


Authors: Cohen, M. A.; Morris, E. A.; Rosen, P. P.; Dershaw, D. D.; Liberman, L.; Abramson, A. F.
Article Title: Pseudoangiomatous stromal hyperplasia: Mammographic, sonographic, and clinical patterns
Abstract: PURPOSE: To analyze the mammographic, ultrasonographic (US), and clinical patterns of pseudoangiomatous stromal hyperplasia (PASH). MATERIALS AND METHODS: Preoperative mammographic and US images, clinical records, and histologic assessments were reviewed in seven cases of PASH as the sole component or dominant stromal component of a clinically or mammographically defined mass lesion. In five, a PASH tumor was diagnosed at image-guided 14- gauge core-needle biopsy; in two, it was diagnosed at surgical excisional biopsy. RESULTS: Four women were premenopausal, two were postmenopausal and one 40-year-old patient had iatrogenic primary amenorrhea. Four of seven masses were palpable; three were discovered at mammography. Four masses enlarged over 6 months to 5 years. At mammography, all masses lacked calcifications; six were well defined, and one was spiculated. One was inapparent at US; the remaining six were well defined and hypoechoic. CONCLUSION: The diagnosis of this rare lesion with image-guided breast biopsy or surgical biopsy is consistent with a well-defined uncalcified mass at mammography and a solid hypoechoic mass at US, usually in a premenopausal woman.
Keywords: adult; middle aged; case report; preoperative evaluation; breast; echomammography; diagnostic imaging; breast neoplasms; biopsy; mammography; hyperplasia; premenopause; postmenopause; breast biopsy; breast diseases; breast disease; ultrasonography, mammary; amenorrhea; humans; human; female; priority journal; article; breast neoplasms, diagnosis; breast, biopsy; breast, diseases
Journal Title: Radiology
Volume: 198
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1996-01-01
Start Page: 117
End Page: 120
Language: English
PUBMED: 8539361
PROVIDER: scopus
DOI: 10.1148/radiology.198.1.8539361
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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MSK Authors
  1. D David Dershaw
    223 Dershaw
  2. Laura Liberman
    176 Liberman
  3. Michael A Cohen
    14 Cohen
  4. Elizabeth A Morris
    336 Morris
  5. Paul P Rosen
    201 Rosen