Radionuclide photon dose kernels for internal emitter dosimetry Journal Article
| Authors: | Furhang, E. E.; Sgouros, G.; Chui, C. S. |
| Article Title: | Radionuclide photon dose kernels for internal emitter dosimetry |
| Abstract: | Photon point dose kernels and absorbed fractions were generated in water for the full photon emission spectrum of each radionuclide of interest in nuclear medicine, by simulating the transport of particles using Monte Carlo. The kernels were then fitted to a mathematical expression. Absorbed fractions for point sources were obtained by integrating the kernels over spheres. Photon dose kernels and absorbed fractions were generated for the following radionuclides: I-123, I-124, I-125, I-131, In-111, Cu-64, Cu-67, Ga-67, Ga- 68, Re-186, Re-188, Sm-153, Sn-117m, Tc-99m. The Monte Carlo simulation was verified by comparing the dose kernels to published monoenergetic photon kernels. Further validation was obtained by generating an I-125 brachytherapy seed kernel and comparing it with published data. Since Monte Carlo simulation was initialized by sampling from the complete photon spectra of these radionuclides, interpolation between monoenergetic kernels and absorbed fractions was not required. The absorbed-fraction due to uniform spherical distributions can be directly applied for use in internal dosimetry. In addition, the kernels can be used as input for three-dimensional internal dosimetry calculations. |
| Keywords: | unclassified drug; technetium 99m; iodine 125; iodine 131; dosimetry; brachytherapy; iodine 124; radioisotope; radioimmunotherapy; energy; indium 111; photon; copper 64; gallium 67; monte carlo; spectrum; absorbed fractions; samarium 153; system analysis; iodine 123; rhenium 188; rhenium 186; tin; copper 67; priority journal; article; internal dosimetry; dose kernels; tin 117m |
| Journal Title: | Medical Physics |
| Volume: | 23 |
| Issue: | 5 |
| ISSN: | 0094-2405 |
| Publisher: | American Association of Physicists in Medicine |
| Date Published: | 1996-05-01 |
| Start Page: | 759 |
| End Page: | 764 |
| Language: | English |
| DOI: | 10.1118/1.597670 |
| PUBMED: | 8724750 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 22 November 2017 -- Source: Scopus |
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