Vocal cord medialization for unilateral paralysis associated with intrathoracic malignancies Journal Article


Authors: Kraus, D. H.; Ali, M. K.; Ginsberg, R. J.; Hughes, C. J.; Orlikoff, R. F.; Rusch, V. W.; Burt, M. E.; McCormack, P. M.; Bains, M. S.
Article Title: Vocal cord medialization for unilateral paralysis associated with intrathoracic malignancies
Abstract: Patients with unilateral vocal cord paralysis from intrathoracic malignancies may have significant dysfunctions of speech, swallowing, ventilation, and effective coughing as a result of inadequate compensation of the nonparalyzed cord. In patients with already compromised pulmonary function, aspiration can be a life-threatening event. Sixty-three patients with intrathoracic malignancies required surgical correction of vocal cord paralysis. Primary pathology included lung cancer (49), esophageal cancer (nine), and miscellaneous tumors (five). Symptoms included hoarseness (62), dyspnea (21), aspiration (26), weight loss (19), dysphagia (14), and pneumonia (14). The surgical procedures included medial displacement of the vocal cord with silicone elastomer (48), temporary Gelfoam injection (seven), and Teflon (polytetrafluoroethylene) injection (eight) to move the affected cord to a medial position. In 11 patients, the operation was performed in the acute postoperative setting to improve pulmonary toilet. Symptomatic improvement was noted in the following proportions of affected patients: hoarseness, 92%; dyspnea, 90%; dysphagia, 93%; aspiration, 92%; pneumonia, 93%; and weight loss, 47%. Overall success rate of the intervention was 57 of 63 patients (90%). All 11 patients treated in the acute setting had immediate improvement. A variety of complications occurred in 17% of patients. Surgical management of vocal cord paralysis in patients with intrathoracic malignancies prevents life-threatening pulmonary complications in the acute postoperative setting. In chronic situations, it provides patients with improved speech, swallowing, and pulmonary function, resulting in improved quality of life, even for patients not cured of their disease.
Keywords: adult; aged; major clinical study; postoperative period; weight reduction; coughing; dysphagia; lung carcinoma; lung function; speech disorder; vocal cord paralysis; esophagus carcinoma; aspiration pneumonia; swallowing; hoarseness; tracheobronchial toilet; human; male; female; priority journal; article
Journal Title: Journal of Thoracic and Cardiovascular Surgery
Volume: 111
Issue: 2
ISSN: 0022-5223
Publisher: Mosby Elsevier  
Date Published: 1996-02-01
Start Page: 334
End Page: 341
Language: English
DOI: 10.1016/s0022-5223(96)70442-7
PUBMED: 8583806
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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MSK Authors
  1. Valerie W Rusch
    864 Rusch
  2. Dennis Kraus
    268 Kraus
  3. Robert J Ginsberg
    178 Ginsberg
  4. Manjit S Bains
    338 Bains
  5. Michael E. Burt
    187 Burt