TTP following ITP in an HIV-positive boy Journal Article
| Authors: | Prasad, V. K.; Kim, I. K.; Farrington, K.; Bussel, J. B. |
| Article Title: | TTP following ITP in an HIV-positive boy |
| Abstract: | Purpose: To report the previously undescribed development of thrombotic thrombocytopenic purpura (TTP) in a human immunodeficiency virus (HIV)- positive child and discuss the differential diagnosis. Patient and Methods: Our patient was a 9-year-old boy with vertically acquired HIV infection and a previous history of immune thrombocytopenic purpura (ITP). Initial presentation, difficulty in diagnosis, clinical course, and subsequent outcome are described. Results: Rapid resolution of TTP following plasmapheresis was seen. Conclusions: Recognition of this treatable though potentially fatal complication in severely ill HIV-infected children requires a high degree of suspicion in view of its diverse clinical manifestations. The long-term outcome may be relatively good. |
| Keywords: | child; treatment outcome; disease course; case report; human immunodeficiency virus infection; thrombocytopenia; immunoglobulin; thrombocyte count; antivirus agent; human immunodeficiency virus; idiopathic thrombocytopenic purpura; acquired immune deficiency syndrome; virus infection; children; cotrimoxazole; epistaxis; thrombotic thrombocytopenic purpura; hiv infections; intravenous drug administration; thrombocyte transfusion; opportunistic infection; zidovudine; platelets; immune thrombocytopenic purpura; aminocaproic acid; purpura, thrombocytopenic, idiopathic; purpura, thrombotic thrombocytopenic; didanosine; rhesus d antibody; humans; human; male; priority journal; article; meprednisone |
| Journal Title: | Journal of Pediatric Hematology/Oncology |
| Volume: | 18 |
| Issue: | 4 |
| ISSN: | 1077-4114 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 1996-11-01 |
| Start Page: | 384 |
| End Page: | 386 |
| Language: | English |
| DOI: | 10.1097/00043426-199611000-00010 |
| PUBMED: | 8888747 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 22 November 2017 -- Source: Scopus |
