Resampling procedures to compare two survival distributions in the presence of right-censored data Journal Article


Authors: Heller, G.; Venkatraman, E. S.
Article Title: Resampling procedures to compare two survival distributions in the presence of right-censored data
Abstract: In this simulation study, the accuracy of the size of four classes of test procedures-asymptotic normal test, permutation test, bootstrap hypothesis test, and bootstrap interval test were compared using the logrank and Prentice-Wilcoxon two sample test statistics. Sample sizes of 20 and 50 per group were used. Twenty observations per group yielded differences in the test procedures. When the Prentice-Wilcoxon test statistic was employed, the asymptotic test procedure was the most accurate; resampling procedures did not improve upon its accuracy. Using the log-rank test statistic, the permutation or bootstrap hypothesis testing procedures were closest to the nominal significance level. The more popular asymptotic normal logrank test was consistently anticonservative. When the number of observations in each group was increased to 50, the test procedures were comparable. Power comparisons were also examined. The test with the greatest power was dependent upon the two survival patterns and the choice of test statistic.
Keywords: statistical analysis; data analysis; biometry; sampling; censored data; bootstrap; article; asymptotic normal test; permutation; two-sample test
Journal Title: Biometrics
Volume: 52
Issue: 4
ISSN: 0006-341X
Publisher: Wiley Blackwell  
Date Published: 1996-12-01
Start Page: 1204
End Page: 1213
Language: English
DOI: 10.2307/2532836
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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  1. Venkatraman Ennapadam Seshan
    382 Seshan
  2. Glenn Heller
    399 Heller