Breast cancer induction due to mammographic screening in hereditarily affected women Journal Article


Authors: Den Otter, W.; Merchant, T. E.; Beijerinck, D.; Koten, J. W.
Article Title: Breast cancer induction due to mammographic screening in hereditarily affected women
Abstract: Breast cancer induction due to mammographic screening has aroused considerable controversy in the discussion of the safety of this procedure. We have attempted to shed some light on this problem by approaching it from both a theoretical and a mathematical point of view. We found that about 99% of mammographically induced breast cancers occur in the group of women who are carriers of a breast cancer gene. Our calculations suggest that in women with an inherited gene for breast cancer an extra tumour in one out of 10 women will be induced by 20 mammographical examinations. On the other hand, mammography is safe for non-gene carriers.
Keywords: breast cancer; models, biological; cancer screening; retinoblastoma; breast neoplasms; time factors; radiation dosage; cancer genetics; mammography; neoplasms, radiation-induced; safety; neoplasms, second primary; neoplastic syndromes, hereditary; eye neoplasms; hereditary cancer; humans; human; female; priority journal; article
Journal Title: Anticancer Research
Volume: 16
Issue: 5B
ISSN: 0250-7005
Publisher: International Institute of Anticancer Research  
Date Published: 1996-09-01
Start Page: 3173
End Page: 3175
Language: English
PUBMED: 8967731
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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