Long-term follow-up after curative surgery for early gastric lymphoma Journal Article
| Authors: | Bartlett, D. L.; Karpeh, M. S. Jr; Filippa, D. A.; Brennan, M. F. |
| Article Title: | Long-term follow-up after curative surgery for early gastric lymphoma |
| Abstract: | Objective: This study was designed to examine the long-term survival of a homogenous group of patients with stage IE or IIE-1 gastric lymphoma after complete surgical resection. Summary Background Data: The management of gastric lymphoma remains controversial. Enthusiasm for multimodality approaches for gastric lymphoma has lead to the current trend of using chemotherapy as primary treatment, thus avoiding gastric resection. Surgery, however, may result in improved long term survival rates. Methods: The records of all patients with the diagnosis of gastric lymphoma from 1980 to 1991 were reviewed retrospectively. Of 106 patients examined, 34 underwent curative resection and regional lymphadenectomy for pathologically staged IE or IIE-1 (pN1) gastric lymphoma. Fifteen patients underwent surgery alone, whereas 19 also received postoperative adjuvant therapy. Results: The median follow-up time was 74 months. The 10-year actuarial disease-free survival was 91% for stage IE disease (n = 23) and 82% for stage IIE-1 disease (n = 11). There were no operative deaths and a 26% morbidity rate. No difference in survival was found for those treated with adjuvant therapy. Conclusions: The results compare favorably to those reported with the use of primary chemotherapy and radiation therapy and suggest that surgery remains the best frontline therapy for early gastric lymphoma. |
| Keywords: | adult; cancer survival; treatment outcome; middle aged; survival analysis; retrospective studies; major clinical study; clinical feature; adjuvant therapy; cancer staging; follow up; follow-up studies; cancer diagnosis; lymph node dissection; risk assessment; early diagnosis; lymphoma; surgical risk; long term care; regression analysis; stomach neoplasms; stomach lymphoma; humans; human; male; female; priority journal; article |
| Journal Title: | Annals of Surgery |
| Volume: | 223 |
| Issue: | 1 |
| ISSN: | 0003-4932 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 1996-01-01 |
| Start Page: | 53 |
| End Page: | 62 |
| Language: | English |
| DOI: | 10.1097/00000658-199601000-00008 |
| PUBMED: | 8554419 |
| PROVIDER: | scopus |
| PMCID: | PMC1235063 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 22 November 2017 -- Source: Scopus |
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