Statistical genetic terminology Journal Article
| Authors: | Elston, R. C.; Satagopan, J.; Sun, S. |
| Article Title: | Statistical genetic terminology |
| Abstract: | Common terms used in statistical genetics with multiple meanings are explained and the terminology used in subsequent chapters is defined. Statistical human genetics has existed as a discipline for over a century, and during that time the meanings of many of the terms used have evolved, largely driven by molecular discoveries, to the point that molecular geneticists, statistical geneticists, and statisticians often have difficulty understanding each other. It is therefore imperative, now that so much of molecular genetics is becoming an in silico and statistical science, that we have a well-defined, common terminology. © 2017, Springer Science+Business Media LLC. |
| Keywords: | mutation; phenotype; allele; gene; genotype; linkage disequilibrium; haplotype; interaction; pleiotropy; quantitative trait locus; penetrance; transformation; phase; polymorphism; epistasis; site; locus; multifactorial; additive; allelic association; codominant; complex trait; diallelic; dominant; gametic phase disequilibrium; identity by descent; identity in state; logit; mixed model; monoallelic; monogenic; monomorphic; multiallelic; multilocus genotype; phenoset; polyallelic; polygenic; probit; recessive; scale of measurement; transition probability; transmission probability; kinship coefficient |
| Journal Title: | Methods in Molecular Biology |
| Volume: | 1666 |
| ISSN: | 1064-3745 |
| Publisher: | Humana Press Inc |
| Date Published: | 2017-01-01 |
| Start Page: | 1 |
| End Page: | 9 |
| Language: | English |
| DOI: | 10.1007/978-1-4939-7274-6_1 |
| PROVIDER: | scopus |
| PUBMED: | 28980238 |
| DOI/URL: | |
| Notes: | Chapter 1 in "Statistical Human Genetics: Methods and Protocols. 2nd ed" (ISBN: 978-1-4939-7273-9) -- Export Date: 2 November 2017 -- Source: Scopus |
