Sentinel lymph node mapping and staging in endometrial cancer: A Society of Gynecologic Oncology literature review with consensus recommendations Journal Article


Authors: Holloway, R. W.; Abu-Rustum, N. R.; Backes, F. J.; Boggess, J. F.; Gotlieb, W. H.; Jeffrey Lowery, W.; Rossi, E. C.; Tanner, E. J.; Wolsky, R. J.
Article Title: Sentinel lymph node mapping and staging in endometrial cancer: A Society of Gynecologic Oncology literature review with consensus recommendations
Abstract: The emphasis in contemporary medical oncology has been “precision” or “personalized” medicine, terms that imply a strategy to improve efficacy through targeted therapies. Similar attempts at precision are occurring in surgical oncology. Sentinel lymph node (SLN) mapping has recently been introduced into the surgical staging of endometrial cancer with the goal to reduce morbidity associated with comprehensive lymphadenectomy, yet obtain prognostic information from lymph node status. The Society of Gynecologic Oncology's (SGO) Clinical Practice Committee and SLN Working Group reviewed the current literature for preparation of this document. Literature-based recommendations for the inclusion of SLN assessment in the treatment of patients with endometrial cancer are presented. This article examines: • History and various techniques of SLN mapping in endometrial cancer• Pathology and clinical outcomes from SLN assessment• Controversies and future directions for research in SLN assessment in endometrial cancer. © 2017 Elsevier Inc.
Keywords: cancer staging; endometrial cancer; lymph node dissection; endometrial neoplasms; neoplasm staging; sentinel lymph node mapping; sentinel lymph node; lymph node excision; sentinel lymph node biopsy; pathology; societies, medical; medical society; consensus development; adenocarcinoma, clear cell; gynecology; literature review; carcinoma, endometrioid; surgical staging; carcinosarcoma; organotechnetium compounds; procedures; surgical oncology; coloring agents; coloring agent; neoplasms, cystic, mucinous, and serous; technetium complex; near infrared spectroscopy; indocyanine green; colorimetry; spectroscopy, near-infrared; humans; human; female; pathology & clinical outcomes; consensus recommendation; single photon emission computed tomography-computed tomography; single photon emission computed tomography computed tomography
Journal Title: Gynecologic Oncology
Volume: 146
Issue: 2
ISSN: 0090-8258
Publisher: Elsevier Inc.  
Date Published: 2017-08-01
Start Page: 405
End Page: 415
Language: English
DOI: 10.1016/j.ygyno.2017.05.027
PUBMED: 28566221
PROVIDER: scopus
PMCID: PMC6075736
DOI/URL:
Notes: Review -- Export Date: 1 November 2017 -- Source: Scopus
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