Innovations in laparoscopic management of endometrial cancer Review


Authors: Bogani, G.; Leitao, M. M.; Ramirez, P. T.; De Vitis, L.; Giudici, A.; Tarantino, V.; Reynolds, E. A.; Mariani, A.
Review Title: Innovations in laparoscopic management of endometrial cancer
Abstract: Introduction: Endometrial cancer is one of the most common gynecologic malignancies, with increasing incidence, in developed countries. Advances in minimally invasive surgery, particularly laparoscopic with or without the use of computer-assisted (‘robotic’) platforms, have transformed its management, improving surgical outcomes and patient recovery. Areas covered: This review explores recent innovations in laparoscopic management of endometrial cancer, including robotic-assisted laparoscopic surgery, sentinel lymph node mapping, and the integration of artificial intelligence in surgical navigation. A comprehensive literature search was conducted using PubMed and clinical trial databases to assess the impact of these advancements on surgical precision, oncologic outcomes, and patient recovery. Major studies comparing robotic-assisted laparoscopy, traditional laparoscopy, and open surgery are reviewed, along with new technologies that support real-time decision-making during surgery. Expert opinion: Minimally invasive approaches have become the standard of care for early-stage endometrial cancer, offering superior perioperative outcomes. While robotic-assisted surgery provides technical advantages, cost and accessibility remain challenges. Sentinel lymph node mapping reduces morbidity compared to full lymphadenectomy, and artificial intelligence holds promise in optimizing surgical precision. Future research should focus on refining these technologies, improving patient selection criteria, and ensuring equitable access to advanced surgical techniques. © 2025 Informa UK Limited, trading as Taylor & Francis Group.
Keywords: endometrial cancer; laparoscopy; artificial intelligence; surgery; robotic
Journal Title: Expert Review of Anticancer Therapy
Volume: 25
Issue: 9
ISSN: 1473-7140
Publisher: Taylor & Francis Group  
Publication status: Published
Date Published: 2025-09-01
Online Publication Date: 2025-06-18
Start Page: 1057
End Page: 1064
Language: English
DOI: 10.1080/14737140.2025.2520965
PROVIDER: scopus
PUBMED: 40519123
DOI/URL:
Notes: Review -- Source: Scopus
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  1. Mario Leitao
    582 Leitao