Initial experience with lung cancer resection after treatment With T-cell checkpoint inhibitors Journal Article


Authors: Chaft, J. E.; Hellmann, M. D.; Velez, M. J.; Travis, W. D.; Rusch, V. W.
Article Title: Initial experience with lung cancer resection after treatment With T-cell checkpoint inhibitors
Abstract: T-cell checkpoint inhibitors targeting the programmed death receptor-1 (PD-1) and its ligand (PD-L1) have recently been approved for the treatment of metastatic non-small cell lung cancer (NSCLC), but their safety and efficacy as neoadjuvant therapy are still undefined. Autoimmune toxicities, notably pneumonitis, are a particular concern in the perioperative setting. This series of 5 cases describes for the first time the safety and technical issues relating to pulmonary resection after checkpoint inhibitor therapy. © 2017 The Society of Thoracic Surgeons
Journal Title: Annals of Thoracic Surgery
Volume: 104
Issue: 3
ISSN: 0003-4975
Publisher: Elsevier Science, Inc.  
Date Published: 2017-09-01
Start Page: e217
End Page: e218
Language: English
DOI: 10.1016/j.athoracsur.2017.03.038
PROVIDER: scopus
PMCID: PMC5572805
PUBMED: 28838509
DOI/URL:
Notes: Article -- Export Date: 2 October 2017 -- Source: Scopus
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  1. Valerie W Rusch
    864 Rusch
  2. Jamie Erin Chaft
    289 Chaft
  3. William D Travis
    743 Travis
  4. Matthew David Hellmann
    411 Hellmann
  5. Moises Velez
    8 Velez