SWI/SNF tumor suppressor gene PBRM1/BAF180 in human clear cell kidney cancer Journal Article
| Authors: | Nargund, A. M.; Osmanbeyoglu, H. U.; Cheng, E. H.; Hsieh, J. J. |
| Article Title: | SWI/SNF tumor suppressor gene PBRM1/BAF180 in human clear cell kidney cancer |
| Abstract: | Mutations within chromatin modulating protein complexes have dominated the novel cancer gene landscape. However, little is known about how individual aberrations contribute to cancer formation. A novel Pbrm1 kidney cancer mouse model examining the role of Pbrm1 provides much needed clue concerning how SWI/SNF complexes might function as tumor suppressors. |
| Keywords: | mtor; vhl; renal-carcinoma; pbrm1; baf180; clear cell kidney cancer mouse model; genomic biomarkers; swi/snf chromatin remodeling tumor suppressor gene |
| Journal Title: | Molecular & Cellular Oncology |
| Volume: | 4 |
| Issue: | 4 |
| ISSN: | 2372-3556 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2017-01-01 |
| Start Page: | e1342747 |
| Language: | English |
| ACCESSION: | WOS:000406853300011 |
| DOI: | 10.1080/23723556.2017.1342747 |
| PROVIDER: | wos |
| PMCID: | PMC5540208 |
| PUBMED: | 28868352 |
| Notes: | Editorial Material -- Source: Wos |
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