| Abstract: |
Cryosurgery of cutaneous lymphoma is rarely used, but is a potentially helpful locally destructive method in selected patients with this malignancy. Patients with primary cutaneous T- cell lymphoma (mycosis fungoides, Sezary syndrome) or disseminated lymphomas of any kind would not be candidates for this treatment approach. The closest precedent for the use of cryosurgery in skin lymphomas may be found in the treatment of conjunctival lymphomas. Cryosurgery for cutaneous lymphoma is appropriate for only a small subset of patients with cutaneous lymphomas, specifically those with low-grade primary cutaneous B cell lymphomas (i.e. primary cutaneous marginal zone lymphoma and primary cutaneous follicle cell lymphoma). Appropriate patients for cryosurgery of skin lymphomas should also have light skin and multiple small skin lesions. In addition, for these selected patients, surgery or radiation therapy would too time-consuming, expensive and/or would have unacceptable cosmetic results. Cryosurgery should be added to the armamentarium of skindirected therapies [surgery, radiation therapy, intralesional injection of corticosteroids or biologic agents] for the treatment of indolent primary cutaneous B cell lymphomas. © Springer-Verlag London 2016. All rights reserved. |
