The SORG nomogram accurately predicts 3- and 12-months survival for operable spine metastatic disease: External validation Journal Article


Authors: Paulino Pereira, N. R.; McLaughlin, L.; Janssen, S. J.; van Dijk, C. N.; Bramer, J. A. M.; Laufer, I.; Bilsky, M. H.; Schwab, J. H.
Article Title: The SORG nomogram accurately predicts 3- and 12-months survival for operable spine metastatic disease: External validation
Abstract: Background and Objectives: Externally validate the SORG12 nomogram and SORG classic algorithm at estimating survival in patients with spine metastatic disease, and compare predictive accuracy with other survival algorithms. Methods: We received data from 100 patients who had surgery for spine metastatic disease at an external institution. Algorithms were accurate if the Area Under Curve (AUC) was >0.70, and we used Receiver Operating Characteristic (ROC) analysis to compare predictive accuracy with other algorithms. Results: The SORG nomogram accurately estimated 3-months (AUC = 0.74) and 12-months survival (AUC = 0.78); it did not accurately estimate 1-month survival (AUC = 0.65). There was no difference in 1-month survival accuracy between the SORG nomogram and SORG classic algorithm (P = 0.162). The SORG nomogram was best at predicting 3-months survival, compared with the Tokuhashi score and SORG classic algorithm (P = 0.009). The SORG nomogram was best at predicting 12-months survival, compared with the Tomita score, Ghori score, Bauer modified score, Tokuhashi score, and SORG classic algorithm (P = 0.033). Conclusions: The SORG nomogram accurately estimated 3- and 12-months survival for operable spine metastatic disease, and is therefore, useful in clinical practice. © 2017 Wiley Periodicals, Inc.
Keywords: algorithms; nomograms; spine; surgery; metastases
Journal Title: Journal of Surgical Oncology
Volume: 115
Issue: 8
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2017-06-15
Start Page: 1019
End Page: 1027
Language: English
DOI: 10.1002/jso.24620
PROVIDER: scopus
PUBMED: 28346699
DOI/URL:
Notes: Article -- Export Date: 1 August 2017 -- Source: Scopus
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  1. Mark H Bilsky
    319 Bilsky
  2. Ilya Laufer
    146 Laufer