Dual phase cone-beam computed tomography in detecting <3 cm hepatocellular carcinomas during transarterial chemoembolization Journal Article


Authors: Wang, X.; Yarmohammadi, H.; Cao, G.; Ji, X.; Hu, J.; Yarmohammadi, H.; Chen, H.; Zhu, X.; Yang, R.; Solomon, S.
Article Title: Dual phase cone-beam computed tomography in detecting <3 cm hepatocellular carcinomas during transarterial chemoembolization
Abstract: Objective: The objective of this study was to evaluate the sensitivity of dual phase cone-beam computed tomography (CBCT) in detecting small (<3 cm in diameter) hepatocellular carcinoma (HCC) tumors during transarterial chemoembolization (TACE). Materials and Methods: Twenty-two consecutive patients with unresectable small HCCs in whom TACE was performed were retrospectively evaluated. Contrast CT or contrast magnetic resonance imaging (MRI) was performed in all patients within 1 month prior to the procedure. Dual phase CBCT was performed prior to TACE and lipiodol-CBCT was performed after treatment. The sensitivity of dual phase CBCT in detecting small HCCs was compared to hepatic angiography, contrast enhanced CT and MRI. Results: Seventy HCC tumors with sizes of < 3 cm were detected in 22 patients. Dual phase CBCT depicted 67 small tumors either on arterial or venous phase and was significantly more sensitive compared to hepatic angiography, contrast CT, or MRI (95.7%, 65.7%, and 71.4%, respectively; P < 0.001). Conclusions: Dual phase CBCT is significantly more sensitive than hepatic angiography, contrast enhanced CT, and MRI in detecting smaller than 3 cm HCC tumors and can be a helpful modality in making accurate planning for treatment of HCC. © 2017 Journal of Cancer Research and Therapeutics.
Keywords: hepatocellular carcinoma; digital subtraction angiography; cone-beam computed tomography; transarterial chemoembolization; hepatic arteriography
Journal Title: Journal of Cancer Research and Therapeutics
Volume: 13
Issue: 1
ISSN: 0973-1482
Publisher: Medknow Publications  
Date Published: 2017-01-01
Start Page: 38
End Page: 43
Language: English
DOI: 10.4103/0973-1482.206242
PROVIDER: scopus
PUBMED: 28508831
DOI/URL:
Notes: Article -- Export Date: 3 July 2017 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Stephen Solomon
    422 Solomon