Dissecting microsatellite instability in colorectal cancer: One size does not fit all Journal Article


Authors: Samstein, R. M.; Chan, T. A.
Article Title: Dissecting microsatellite instability in colorectal cancer: One size does not fit all
Abstract: Microsatellite instability (MSI) marks distinct subsets of tumors in many cancer types and is caused by mutations in genes required for mismatch repair. A recent report analyses the molecular foundations of MSI-positive colorectal cancers and reveals substantial molecular heterogeneity, which might have consequences for the potential use of immunotherapy in MSI-positive cancers. © 2017 The Author(s).
Journal Title: Genome Medicine
Volume: 9
ISSN: 1756-994X
Publisher: Biomed Central Ltd  
Date Published: 2017-05-24
Start Page: 45
Language: English
DOI: 10.1186/s13073-017-0438-9
PROVIDER: scopus
PMCID: PMC5442871
PUBMED: 28539127
DOI/URL:
Notes: Article -- Export Date: 3 July 2017 -- Source: Scopus
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  1. Timothy Chan
    317 Chan