Authors: | Samstein, R. M.; Chan, T. A. |
Article Title: | Dissecting microsatellite instability in colorectal cancer: One size does not fit all |
Abstract: | Microsatellite instability (MSI) marks distinct subsets of tumors in many cancer types and is caused by mutations in genes required for mismatch repair. A recent report analyses the molecular foundations of MSI-positive colorectal cancers and reveals substantial molecular heterogeneity, which might have consequences for the potential use of immunotherapy in MSI-positive cancers. © 2017 The Author(s). |
Journal Title: | Genome Medicine |
Volume: | 9 |
ISSN: | 1756-994X |
Publisher: | Biomed Central Ltd |
Date Published: | 2017-05-24 |
Start Page: | 45 |
Language: | English |
DOI: | 10.1186/s13073-017-0438-9 |
PROVIDER: | scopus |
PMCID: | PMC5442871 |
PUBMED: | 28539127 |
DOI/URL: | |
Notes: | Article -- Export Date: 3 July 2017 -- Source: Scopus |