Locally recurrent lentigo maligna and lentigo maligna melanoma: Characteristics and time to recurrence after surgery Journal Article


Authors: Connolly, K. L.; Hibler, B. P.; Lee, E. H.; Rossi, A. M.; Busam, K. J.; Nehal, K. S.
Article Title: Locally recurrent lentigo maligna and lentigo maligna melanoma: Characteristics and time to recurrence after surgery
Abstract: BACKGROUND Various studies have reported local recurrence (LR) rates after surgical treatment of lentigo maligna (LM) and lentigo maligna melanoma (LMM). However, the time to LR of LM/LMM is not currently known, as few studies report time to LR and have long-term follow-up. OBJECTIVE To define time to LR in LM/LMM after surgical treatment, and to describe features of observed LR. MATERIALS AND METHODS Retrospective single-center study of consecutive patients presenting with locally recurrent LM/LMM. RESULTS Six hundred forty-nine cases of LM/LMM were reviewed; 29 (21 LM, and 8 LMM) of 41 locally recurrent cases had original histology reports and were included. The mean time to LR was 57.5 months (range 7-194). For cases presenting as primary LM, LR was also in situ in 14/21 (67%) of cases. Seven of 21 LM recurred as LMM. Of the 8 primary LMM, 3/8 (37.5%) presented with subsequent LMM and all were slightly deeper on re-excision. CONCLUSION The mean time to LR of LM/LMM is at least 57.5 months, underscoring the importance of long-term follow-up. Seven of 21 LM recurred as invasive disease, but the lack of development of LMM from LM in most recurrent cases confirms LM is slowly progressive. © 2017 by the American Society for Dermatologic Surgery, Inc. All rights reserved.
Journal Title: Dermatologic Surgery
Volume: 43
Issue: 6
ISSN: 1076-0512
Publisher: Lippincott Williams & Wilkins  
Date Published: 2017-06-01
Start Page: 792
End Page: 797
Language: English
DOI: 10.1097/dss.0000000000001118
PROVIDER: scopus
PUBMED: 28296789
DOI/URL:
Notes: Article -- Export Date: 3 July 2017 -- Source: Scopus
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MSK Authors
  1. Kishwer S Nehal
    278 Nehal
  2. Erica H Lee
    135 Lee
  3. Klaus J Busam
    688 Busam
  4. Anthony Rossi
    233 Rossi
  5. Brian Phillip Hibler
    55 Hibler