Helicase structures: A new twist on DNA unwinding Journal Article
| Author: | Marians, K. J. |
| Article Title: | Helicase structures: A new twist on DNA unwinding |
| Abstract: | The crystal structures of two members of the SF1 family of helicases, Rep and PcrA, and one member of the SF2 family of helicases, the HCV RNA helicase, have recently been solved. These structures illuminate the roles of the conserved helicase motifs in catalytic function and offer clues as to how these proteins can translocate along DNA. |
| Keywords: | dna binding protein; dna-binding proteins; molecular genetics; protein conformation; metabolism; bacteria (microorganisms); bacterial protein; chemistry; bacterial proteins; dna; amino acid sequence; conserved sequence; molecular sequence data; nucleotide sequence; transactivator protein; short survey; models, molecular; crystallography, x-ray; chemical structure; trans-activators; helicase; catalysis; protein secondary structure; hepatitis c virus; x ray crystallography; protein structure, secondary; dna helicases; pcra protein, bacteria; replication initiator protein |
| Journal Title: | Structure |
| Volume: | 5 |
| Issue: | 9 |
| ISSN: | 0969-2126 |
| Publisher: | Cell Press |
| Date Published: | 1997-09-15 |
| Start Page: | 1129 |
| End Page: | 1134 |
| Language: | English |
| PUBMED: | 9331421 |
| PROVIDER: | scopus |
| DOI: | 10.1016/S0969-2126(97)00263-3 |
| DOI/URL: | |
| Notes: | Short Survey -- Export Date: 17 March 2017 -- Source: Scopus |
