Helicase structures: A new twist on DNA unwinding Journal Article


Author: Marians, K. J.
Article Title: Helicase structures: A new twist on DNA unwinding
Abstract: The crystal structures of two members of the SF1 family of helicases, Rep and PcrA, and one member of the SF2 family of helicases, the HCV RNA helicase, have recently been solved. These structures illuminate the roles of the conserved helicase motifs in catalytic function and offer clues as to how these proteins can translocate along DNA.
Keywords: dna binding protein; dna-binding proteins; molecular genetics; protein conformation; metabolism; bacteria (microorganisms); bacterial protein; chemistry; bacterial proteins; dna; amino acid sequence; conserved sequence; molecular sequence data; nucleotide sequence; transactivator protein; short survey; models, molecular; crystallography, x-ray; chemical structure; trans-activators; helicase; catalysis; protein secondary structure; hepatitis c virus; x ray crystallography; protein structure, secondary; dna helicases; pcra protein, bacteria; replication initiator protein
Journal Title: Structure
Volume: 5
Issue: 9
ISSN: 0969-2126
Publisher: Cell Press  
Date Published: 1997-09-15
Start Page: 1129
End Page: 1134
Language: English
PUBMED: 9331421
PROVIDER: scopus
DOI: 10.1016/S0969-2126(97)00263-3
DOI/URL:
Notes: Short Survey -- Export Date: 17 March 2017 -- Source: Scopus
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  1. Kenneth Marians
    127 Marians