Comparative analysis of intranodal lymphangiography with percutaneous intervention for postsurgical chylous effusions Journal Article


Authors: Yannes, M.; Shin, D.; McCluskey, K.; Varma, R.; Santos, E.
Article Title: Comparative analysis of intranodal lymphangiography with percutaneous intervention for postsurgical chylous effusions
Abstract: Purpose: To evaluate clinical success and time to resolution of intranodal lymphangiography (INL) alone or with thoracic duct embolization (TDE) or thoracic duct disruption (TDD) based on initial effusion volume for postsurgical chylothorax. Materials and Methods: Retrospective review was performed of 57 patients (mean age 63 y; 65% male) undergoing INL alone or in conjunction with other percutaneous techniques for postsurgical chylous effusions. INL alone was performed when chylothorax output was <= 500 mL/d'and no leak was identified during fluoroscopy. Results: INL. as technically successful in all patients. There was 1 major and 2 minor complications. Clinical success rate was 71% (40/56). Clinical success rate meeting algorithm inclusion criteria was 71.4% (5/7) for INL only, 41.7% (5112) in INL with TDD, and 90.5% (19/21) in INL with TDE. Hazard ratio (HR) of clinical success of INL with TDE versus INL only was not statistically significant (HR 2.3, 95% confidence interval [CI], 0.70-5.87, P =.19). Median time to resolution was 14 days for INL only (95% CI, 0 days to not reached), 7 days for INL with TDD (95% CI, 4 days to not reached), and 3 days for INL with TDE (95% CI, 2 to 5 days) (P=.007). No statistically significant difference in median time to resolution existed between INL with TDE and INL only (P =.04). Conclusion: In patients with postsurgical chylothorax, INL alone had similar rates of clinical success and time to resolution compared with INL with TDE when initial effusion volume was <= 500 mL/d and no leak was visualized during fluoroscopy.
Keywords: experience; postoperative; management; lymph-node dissection; strategy; disruption; feasibility; chylothorax; pulmonary resection; leakage; thoracic-duct embolization
Journal Title: Journal of Vascular and Interventional Radiology
Volume: 28
Issue: 5
ISSN: 1051-0443
Publisher: Elsevier Science, Inc.  
Date Published: 2017-05-01
Start Page: 704
End Page: 711
Language: English
ACCESSION: WOS:000400537400011
DOI: 10.1016/j.jvir.2016.12.1209
PROVIDER: wos
PUBMED: 28169139
Notes: Article -- Source: Wos
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