Authors: | Howe, J. R.; Guillem, J. G. |
Article Title: | The genetics of colorectal cancer |
Abstract: | This article reviews the genetic alterations that are thought to play a role in the development of sporadic and hereditary forms of colorectal cancer. It also highlights their potential utility in clinical practice, especially in the field of presymptomatic diagnostic testing for hereditary forms of colorectal cancer. |
Keywords: | human tissue; human cell; mutation; review; pathophysiology; colorectal cancer; phenotype; genotype; protein p53; dna methylation; colorectal neoplasms; cancer genetics; disease progression; genes, ras; genetic screening; adenomatous polyp; genes, p53; colon carcinogenesis; dna ligases; base mispairing; adenomatous polyposis coli; gene isolation; genes, apc; humans; human; priority journal |
Journal Title: | Surgical Clinics of North America |
Volume: | 77 |
Issue: | 1 |
ISSN: | 0039-6109 |
Publisher: | Elsevier Inc. |
Date Published: | 1997-02-01 |
Start Page: | 175 |
End Page: | 195 |
Language: | English |
DOI: | 10.1016/s0039-6109(05)70538-7 |
PUBMED: | 9092109 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Export Date: 17 March 2017 -- Source: Scopus |