Methodological issues in the use of tumour markers in cancer epidemiology Journal Article
| Authors: | Zhang, Z. F.; Cordon-Cardo, C.; Rothman, N.; Freedman, A. N.; Taylor, J. A. |
| Article Title: | Methodological issues in the use of tumour markers in cancer epidemiology |
| Abstract: | In this chapter, we review major methodological and practical issues associated with the use of tumour markers. At this stage of development, studies with a combination of tumour, susceptibility and exposure markers are needed to illustrate the link between exposure and biological response and to assess the interactive effects of tumour susceptibility markers in this process. Several practical issues related to the application of tumour markers are discussed, including banking of tumour tissue, setting a laboratory strategy and performing etiological heterogeneity analysis. |
| Keywords: | case control study; case-control studies; review; methodology; neoplasm; neoplasms; tumor markers, biological; tumor marker; statistical analysis; data interpretation, statistical; epidemiologic methods; epidemiology; tissue preservation; humans; human |
| Journal Title: | IARC Scientific Publications |
| Issue: | 142 |
| ISSN: | 0300-5038 |
| Publisher: | International Agency for Research on Cancer |
| Date Published: | 1997-01-01 |
| Start Page: | 201 |
| End Page: | 213 |
| Language: | English |
| PUBMED: | 9354920 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Chapter in "Application of Biomarkers in Cancer Epidemiology" (ISBN: 9283221427) -- Source: Scopus |
