| Abstract: |
Commercial sunscreens based on nanoparticles containing TiO2 and ZnO are widely accepted to offer effective UV coverage and a more cosmetically elegant formulation. New organic filters are also being combined into modern sunscreens based on photostabilizing technologies to expand the options for broad-spectrum sunscreen coverage. The nanosized filters offer advantages, yet the same qualities have also drawn concern. There is a theoretical risk that percutaneous penetration of nanomaterials through the skin may generate toxicity, damage the upper layers of the skin and potentially have systemic absorption. These issues can hamper the regulatory approval of these ingredients by cosmetic and drug agencies around the world. This book chapter will explore all of these topics to better understand this promising technology as it relates to photoprotection and sunscreen products. © 2016 Elsevier Inc. |
