Ovarian and uterine disease in women with colorectal cancer Journal Article
| Authors: | Abu-Rustum, N. R.; Barakat, R. R.; Curtin, J. P. |
| Article Title: | Ovarian and uterine disease in women with colorectal cancer |
| Abstract: | Objective: To identify the nature of adnexal and uterine disease in women with a history of colorectal adenocarcinoma who develop new pelvic masses or uterine cancers during follow-up. Methods: We conducted a retrospective chart review of the Memorial Hospital Gynecology Service database and identified 50 women, each with a history of colorectal carcinoma who underwent a hysterectomy or adnexectomy between January 1, 1977, and February 29, 1996. Subject characteristics, indications for re-operation, and findings at surgery were recorded. Results: The mean age at re-operation was 66 years (range, 37-76), with a median interval from initial diagnosis to re- operation of 25 months (range, 3-444). Indications for re-operation were: 1) new pelvic mass in 35 women, and 2) cancer on endometrial or cervical biopsy in 15. Twenty-six of the 35 (74%) women who presented with a pelvic mass had a malignancy in the ovary, with metastatic colon cancer noted in 20 of 26 (77%) women, and epithelial ovarian cancer in six of 26 (23%). The mean ovarian tumor size for metastatic colorectal carcinoma, ovarian cancer, and benign tumors was 15, 8, and 6 cm, respectively. Fifteen women underwent hysterectomy for a newly diagnosed cancer in the uterus, with the majority, 11 (73%), having endometrial adenocarcinoma, followed by metastatic colon cancer to the endometrium or cervix in three (20%) women, and primary cervical carcinoma in one. Conclusion: Women with a history of colorectal cancer who underwent adnexectomy for a new pelvic mass had metastatic colon cancer to the ovary in 57%, benign ovarian neoplasm in 26%, and primary ovarian cancer in 17% of cases. Women who underwent hysterectomy for a newly diagnosed carcinoma in the uterus had primary endometrial adenocarcinoma in 73% and metastatic colon cancer in 20% of cases. |
| Keywords: | adult; clinical article; human tissue; aged; middle aged; retrospective studies; follow up; endometrium carcinoma; hysterectomy; colorectal cancer; adenocarcinoma; ovarian neoplasms; colorectal neoplasms; reoperation; ovary metastasis; uterus cancer; uterine neoplasms; uterine cervix biopsy; endometrium biopsy; uterus disease; adnexa disease; ovary disease; humans; human; female; priority journal; article |
| Journal Title: | Obstetrics and Gynecology |
| Volume: | 89 |
| Issue: | 1 |
| ISSN: | 0029-7844 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 1997-01-01 |
| Start Page: | 85 |
| End Page: | 87 |
| Language: | English |
| DOI: | 10.1016/s0029-7844(96)00369-9 |
| PUBMED: | 8990444 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 17 March 2017 -- Source: Scopus |
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890Abu-Rustum
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