Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma Journal Article


Authors: El-Shirbiny, A. M.; Yeung, H.; Imbriaco, M.; Michaeli, J.; Macapinlac, H.; Larson, S. M.
Article Title: Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma
Abstract: Experience of scintigraphic detection of bone lesion and active bone marrow involvement of multiple myeloma, especially with sestamibi and FDG- PET scans is in evolution. We report a case of intense sestamibi uptake in bone marrow correlating with the extent of the disease, while FDG-PET scans showed activity only in areas of active disease progression associated with pain. Technetium-99m-sestamibi appears to indicate the extent of the disease, while [18F]FDG-PET scans show sites of active tumor proliferation and may be useful in directing local therapy such as radiation.
Keywords: aged; case report; positron emission tomography; radiopharmaceuticals; tumor localization; multiple myeloma; anemia; cancer pain; bone marrow biopsy; fluorodeoxyglucose f 18; fluorodeoxyglucose f18; methoxy isobutyl isonitrile technetium tc 99m; pet; leg pain; tomography, emission-computed; technetium tc 99m sestamibi; fluorine radioisotopes; sestamibi; deoxyglucose; humans; human; male; priority journal; article; fluorine-18-fdg
Journal Title: Journal of Nuclear Medicine
Volume: 38
Issue: 8
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 1997-08-01
Start Page: 1208
End Page: 1210
Language: English
PUBMED: 9255151
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
Citation Impact
MSK Authors
  1. Henry W D Yeung
    126 Yeung
  2. Steven M Larson
    958 Larson