ERS-24, a mammalian v-SNARE implicated in vesicle traffic between the ER and the Golgi Journal Article

   


Authors: Paek, I.; Orci, L.; Ravazzola, M.; Erdjument-Bromage, H.; Amherdt, M.; Tempst, P.; Söllner, T. H.; Rothman, J. E.
Article Title: ERS-24, a mammalian v-SNARE implicated in vesicle traffic between the ER and the Golgi
Abstract: We report the identification and characterization of ERS-24 (Endoplasmic Reticulum SNARE of 24 kD), a new mammalian v-SNARE implicated in vesicular transport between the ER and the Golgi. ERS-24 is incorporated into 20S docking and fusion particles and disassembles from this complex in an ATP- dependent manner. ERS-24 has significant sequence homology to Sec22p, a v- SNARE in Saccharomyces cerevisiae required for transport between the ER and the Golgi. ERS-24 is localized to the ER and to the Golgi, and it is enriched in transport vesicles associated with these organelles.
Keywords: nonhuman; binding affinity; animal cell; mammalia; animals; nerve tissue proteins; protein binding; membrane proteins; tumor cells, cultured; animalia; cloning, molecular; endoplasmic reticulum; molecular sequence data; sequence homology, amino acid; hybrid protein; saccharomyces cerevisiae; mammal; carrier proteins; cell membrane; base sequence; rats; cell transport; mammals; adenosine triphosphatases; biological transport; exocytosis; cho cells; cricetinae; fungal proteins; vesicular transport proteins; qa-snare proteins; golgi apparatus; r-snare proteins; snare proteins; microscopy, immunoelectron; priority journal; article; soluble n-ethylmaleimide-sensitive factor attachment proteins; leukemia, basophilic, acute
Journal Title: Journal of Cell Biology
Volume: 137
Issue: 5
ISSN: 0021-9525
Publisher: Rockefeller University Press  
Date Published: 1997-06-02
Start Page: 1017
End Page: 1028
Language: English
DOI: 10.1083/jcb.137.5.1017
PUBMED: 9166403
PROVIDER: scopus
PMCID: PMC2136225
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030958964&doi=10.1083%2fjcb.137.5.1017&partnerID=40&md5=d8a32ee607e966e0cde7e9a6d268d306
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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MSK Authors
  1. Thomas H Sollner
    65 Sollner
  2. James E Rothman
    120 Rothman
  3. Paul J Tempst
    324 Tempst
  4. Hediye Erdjument-Bromage
    271 Erdjument-Bromage
  5. Inbok Paek
    4 Paek
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