Hepatocellular adenoma among adult survivors of childhood and young adult cancer Journal Article


Authors: Tonorezos, E. S.; Barnea, D.; Abou-Alfa, G. K.; Bromberg, J.; D'Angelica, M.; Sklar, C. A.; Shia, J.; Oeffinger, K. C.
Article Title: Hepatocellular adenoma among adult survivors of childhood and young adult cancer
Abstract: Hepatocellular adenoma (HCA) is a rare benign epithelial neoplasm with potential for hemorrhage, rupture, or malignant transformation. Reported annual incidence of HCA is approximately 1/1,000,000. We identified 12 cases of HCA among adults with a history of childhood or young adult cancer. The most common cancer diagnosis was leukemia (N = 4). Five had undergone allogeneic hematopoietic stem cell transplant with total body irradiation. All 11 females had prior estrogen therapy; the male case was hypogonadal. This report suggests childhood and young adult cancer survivors may be at increased risk for HCA, but further investigation is needed. © 2016 Wiley Periodicals, Inc.
Keywords: childhood cancer; survivor; hepatoma; hepatocellular adenoma
Journal Title: Pediatric Blood and Cancer
Volume: 64
Issue: 4
ISSN: 1545-5009
Publisher: Wiley Periodicals, Inc  
Date Published: 2017-04-01
Start Page: e26294
Language: English
DOI: 10.1002/pbc.26294
PROVIDER: scopus
PUBMED: 27781382
PMCID: PMC5477223
DOI/URL:
Notes: Article -- Export Date: 2 March 2017 -- Source: Scopus
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MSK Authors
  1. Charles A Sklar
    303 Sklar
  2. Jacqueline Bromberg
    113 Bromberg
  3. Ghassan Abou-Alfa
    328 Abou-Alfa
  4. Kevin Oeffinger
    286 Oeffinger
  5. Jinru Shia
    542 Shia
  6. Dana   Barnea
    9 Barnea