Pseudomalignant heterotopic ossification: Differential diagnosis and report of two cases Journal Article


Authors: Kaplan, F. S.; Gannon, F. H.; Hahn, G. V.; Wollner, N.; Prauner, R.
Article Title: Pseudomalignant heterotopic ossification: Differential diagnosis and report of two cases
Abstract: Pseudomalignant heterotopic ossification is a rare, self limited connective tissue disorder of unknown origin that may occur atypically during childhood and can simulate either soft tissue sarcoma or fibrodysplasia ossificans progressiva. A complex constellation of diagnostic features usually enable the differentiation of pseudomalignant heterotopic ossification from extraosseous osteosarcoma and fibrodysplasia ossificans progressiva during a time span of approximately 8 to 12 weeks. Orthopaedic surgeons who treat children with connective tissue tumors should be familiar with pseudomalignant heterotopic ossification and its differential diagnosis. The occasional mild and variable expression of fibrodysplasia ossificans progressiva rarely may make it more difficult to distinguish from pseudomalignant heterotopic ossification. It is possible that pseudomalignant heterotopic ossification is a fomre fruste of fibrodysplasia ossificans progressiva.
Keywords: osteosarcoma; child; child, preschool; clinical feature; case report; conference paper; diagnosis, differential; differential diagnosis; tomography, x-ray computed; fever; malaise; soft tissue sarcoma; pseudotumor; irritability; heterotopic ossification; ossifying myositis; humans; human; female; priority journal; ossification, heterotopic; myositis ossificans
Journal Title: Clinical Orthopaedics and Related Research
Volume: 346
ISSN: 0009-921X
Publisher: Springer  
Date Published: 1998-01-01
Start Page: 134
End Page: 140
Language: English
PUBMED: 9577421
PROVIDER: scopus
DOI/URL:
Notes: Conference Paper -- Export Date: 12 December 2016 -- Source: Scopus
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