Osteosarcoma Journal Article
| Author: | La Quaglia, M. P. |
| Article Title: | Osteosarcoma |
| Abstract: | The survival rate of patients with osteogenic sarcoma has greatly improved with the institution of a multidisciplinary approach that combines multi-agent chemotherapy and limb-sparing surgery. Presently, 80% of those patients who do not have distant metastases at presentation will become long- term survivors, compared to 20% prior to 1970. For patients with metastases at diagnosis, or who develop metastases after initiation of treatment, long- term survival is also possible if all primary and metastatic disease is removed. The data presented in this article supports aggressive resection of pulmonary metastases in osteogenic sarcoma patients. |
| Keywords: | osteosarcoma; cancer survival; treatment outcome; bone neoplasms; bone tumor; surgical technique; survival rate; clinical trial; review; cisplatin; doxorubicin; multimodality cancer therapy; comparative study; combined modality therapy; nuclear magnetic resonance imaging; positron emission tomography; antineoplastic agent; metastasis; computer assisted tomography; lung lobectomy; lung resection; thoracotomy; antineoplastic combined chemotherapy protocols; lung neoplasms; pneumonectomy; tomography, x-ray computed; cyclophosphamide; ifosfamide; lung tumor; lung metastasis; membrane protein; radiography; thorax radiography; neoplasms, second primary; second cancer; endoscopy; cell adhesion; integrin; thoracoscopy; bone scintiscanning; narcotic agent; cell adhesion molecule; humans; human; priority journal |
| Journal Title: | Chest Surgery Clinics of North America |
| Volume: | 8 |
| Issue: | 1 |
| ISSN: | 1052-3359 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1998-02-01 |
| Start Page: | 77 |
| End Page: | 95 |
| Language: | English |
| PUBMED: | 9515174 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 12 December 2016 -- Source: Scopus |
