The effect of the USPSTF PSA screening recommendation on prostate cancer incidence patterns in the USA Journal Article


Authors: Fleshner, K.; Carlsson, S. V.; Roobol, M. J.
Article Title: The effect of the USPSTF PSA screening recommendation on prostate cancer incidence patterns in the USA
Abstract: Guidelines regarding recommendations for PSA screening for early detection of prostate cancer are conflicting. In 2012, the United States Preventive Services Task Force (USPSTF) assigned a grade of D (recommending against screening) for men aged ≥75 years in 2008 and for men of all ages in 2012. Understanding temporal trends in rates of screening before and after the 2012 recommendation in terms of usage patterns in PSA screening, changes in prostate cancer incidence and biopsy patterns, and how the recommendation has influenced physician's and men's attitudes about PSA screening and subsequent ordering of other screening tests is essential within the scope of prostate cancer screening policy. Since the 2012 recommendation, rates of PSA screening decreased by 3-10% in all age groups and across most geographical regions of the USA. Rates of prostate biopsy and prostate cancer incidence have declined in unison, with a shift towards tumours being of higher grade and stage upon detection. Despite the recommendation, some physicians report ongoing willingness to screen appropriately selected men, and many men report intending to continue to ask for the PSA test from their physician. In the coming years, we expect to have an improved understanding of whether these decreased rates of screening will affect prostate cancer metastasis and mortality. © 2016 Macmillan Publishers Limited. All rights reserved.
Journal Title: Nature Reviews Urology
Volume: 14
Issue: 1
ISSN: 1759-4812
Publisher: Nature Publishing Group  
Date Published: 2017-01-01
Start Page: 26
End Page: 37
Language: English
DOI: 10.1038/nrurol.2016.251
PROVIDER: scopus
PUBMED: 27995937
PMCID: PMC5341610
DOI/URL:
Notes: Review -- Export Date: 2 February 2017 -- Source: Scopus
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  1. Sigrid Viktoria Carlsson
    220 Carlsson