The role of interventional radiology in the treatment of intrahepatic cholangiocarcinoma Journal Article


Authors: Ierardi, A. M.; Angileri, S. A.; Patella, F.; Panella, S.; Lucchina, N.; Petre, E. N.; Pinto, A.; Franceschelli, G.; Carrafiello, G.; Cornalba, G.; Sofocleous, C. T.
Article Title: The role of interventional radiology in the treatment of intrahepatic cholangiocarcinoma
Abstract: Intrahepatic cholangiocarcinoma (ICC) is the second most common primary hepatic malignancy after hepatocellular carcinoma. Complete surgical resection remains the only potentially curative option for patients with ICC. However, until now, early diagnosis with potential surgical intervention has been the exception rather than the rule with only 30% of patients qualifying for attempted surgical cure. Many patients are unresectable because of disease stage, anatomic conditions, medical comorbidities, and small future remnant liver. Interventional radiology procedures are available for these types of patients with intra-arterial therapies and/or ablative treatments both for curative and for palliative treatment. The goals of interventional therapy are to control local tumor growth, to relieve symptoms, and to improve and preserve quality of life. The choice of treatment depends largely on tumor extent and patient performance. No randomized studies exist to compare treatments. The present review describes the current evidence of the interventional treatments in the management of the ICC. Moreover, interventional procedures available to increase the future liver reserve before surgery were analyzed. © 2016, Springer Science+Business Media New York.
Keywords: interventional radiology; intrahepatic cholangiocarcinoma; radioembolization; palliative treatment; ablative treatments; intra-arterial therapies
Journal Title: Medical Oncology
Volume: 34
Issue: 1
ISSN: 1357-0560
Publisher: Humana Press Inc  
Date Published: 2017-01-01
Start Page: 11
Language: English
DOI: 10.1007/s12032-016-0866-1
PROVIDER: scopus
PUBMED: 28008570
DOI/URL:
Notes: Article -- Export Date: 2 February 2017 -- Source: Scopus
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  1. Elena Nadia Petre
    108 Petre