Success of an international learning health care system in hematopoietic cell transplantation: The American Society of Blood and Marrow Transplantation Clinical Case Forum Journal Article


Authors: Barba, P.; Burns, L. J.; Litzow, M. R.; Juckett, M. B.; Komanduri, K. V.; Lee, S. J.; Devlin, S. M.; Costa, L. J.; Khan, S.; King, A.; Klein, A.; Krishnan, A.; Malone, A.; Mir, M. A.; Moravec, C.; Selby, G.; Roy, V.; Cochran, M.; Stricherz, M. K.; Westmoreland, M. D.; Perales, M. A.; Wood, W. A.
Article Title: Success of an international learning health care system in hematopoietic cell transplantation: The American Society of Blood and Marrow Transplantation Clinical Case Forum
Abstract: The American Society for Blood and Marrow Transplantation (ASBMT) Clinical Case Forum (CCF) was launched in 2014 as an online secure tool to enhance interaction and communication among hematopoietic cell transplantation (HCT) professionals worldwide through the discussion of challenging clinical care issues. After 14 months, we reviewed clinical and demographical data of cases posted in the CCF from January 29, 2014 to March 18, 2015. A total of 137 cases were posted during the study period. Ninety-two cases (67%) were allogeneic HCT, 29 (21%) were autologous HCT, and in 16 (12%), the type of transplantation (autologous versus allogeneic) was still under consideration. The diseases most frequently discussed included non-Hodgkin lymphoma (NHL; n = 30, 22%), acute myeloid leukemia (n = 23, 17%), and multiple myeloma (MM; n = 20, 15%). When compared with the US transplantation activity reported by the US Department of Health and Human Services, NHL and acute lymphoblastic leukemia cases were over-represented in the CCF, whereas MM was under-represented (P <.001). A total of 259 topics were addressed in the CCF with a median of 2 topics/case (range, 1 to 6). Particularly common topics included whether transplantation was indicated (n = 57, 41%), conditioning regimen choice (n = 44, 32%), and post-HCT complications after day 100 (n = 43, 31%). The ASBMT CCF is a successful tool for collaborative discussion of complex cases in the HCT community worldwide and may allow identification of areas of controversy or unmet need from clinical, educational and research perspectives. © 2016 American Society for Blood and Marrow Transplantation
Keywords: autologous stem cell transplantation; allogeneic hematopoietic stem cell transplantation; case discussions
Journal Title: Biology of Blood and Marrow Transplantation
Volume: 22
Issue: 3
ISSN: 1083-8791
Publisher: Elsevier Inc.  
Date Published: 2016-03-01
Start Page: 564
End Page: 570
Language: English
DOI: 10.1016/j.bbmt.2015.12.008
PROVIDER: scopus
PMCID: PMC4965270
PUBMED: 26718665
DOI/URL:
Notes: Article -- Export Date: 2 February 2017 -- Source: Scopus
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  1. Miguel-Angel Perales
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  2. Sean McCarthy Devlin
    601 Devlin