Carotid body paraganglioma metastatic to bone: Report of two cases Journal Article
| Authors: | Kawai, A.; Healey, J. H.; Wilson, S. C.; Huvos, A. G.; Yeh, S. D. J. |
| Article Title: | Carotid body paraganglioma metastatic to bone: Report of two cases |
| Abstract: | Two patients with carotid body paraganglioma developed bone metastases 3 and 6 years respectively after surgical excision of the primary tumors. Plain radiographs showed ill defined metastatic lesions. Scintigram using radiolabeled metaiodobenzylguanidine, an analogue of noradrenaline that is taken up by neurosecretary granules, showed an abnormal accumulation in the corresponding metastatic lesion. Histologically, nests of epithelioid cells with clear cytoplasm and pyknotic nuclei and abundant collagen fibers wereobserved within destroyed trabeculae. Treatment including external radiation and surgery provided pain relief and early local disease control. |
| Keywords: | adult; bone neoplasms; middle aged; clinical feature; case report; bone metastasis; paraganglioma; computer assisted tomography; time; (3 iodobenzyl)guanidine; cytoplasm; cancer control; epithelioid cell; bone scintiscanning; bone radiography; carotid body tumor; collagen fiber; humans; human; male; priority journal; article; bone iodine-131 metaiodobenzylguanidine radiation surgery; paraganglioma metastasis |
| Journal Title: | Skeletal Radiology |
| Volume: | 27 |
| Issue: | 2 |
| ISSN: | 0364-2348 |
| Publisher: | Springer |
| Date Published: | 1998-02-01 |
| Start Page: | 103 |
| End Page: | 107 |
| Language: | English |
| DOI: | 10.1007/s002560050346 |
| PUBMED: | 9526777 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 12 December 2016 -- Source: Scopus |
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