Paternity in men with stage I testis tumors on surveillance Journal Article


Authors: Herr, H. W.; Bar-Chama, N.; O'Sullivan, M.; Sogani, P. C.
Article Title: Paternity in men with stage I testis tumors on surveillance
Abstract: Purpose: We report long-term paternity in men with stage I testis tumors who were managed initially by surveillance. Patients and Methods: One hundred five patients with clinical stage I nonseminomatous germ cell tumors of the testis were entered on a surveillance protocol and followed up for more than 10 years. Actual fertility potential was assessed by pregnancy. Results: Of the 105 patients, 41 (39%) have fathered children, which includes 36 of 78 (46%) patients while on active surveillance and five of 27 (19%) patients after treatment for relapse. Of 63 couples who attempted a pregnancy on surveillance or were presumed capable of impregnation (whether they tried or not), 41 (65%) were successful. Conclusion: These results show that the majority of men with stage I testis tumor who are on surveillance after orchiectomy, have a suitable partner, and attempt impregnation achieve a successful pregnancy. Pregnancy rates appear to be less than reported in men who have a nerve-sparing retroperitoneal lymph node dissection (RPLND) because more patients on surveillance require treatment for relapse, which reduces their chances for pregnancy.
Keywords: adolescent; adult; middle aged; major clinical study; cancer staging; follow-up studies; preoperative evaluation; lymph node excision; recurrence; testis tumor; testicular neoplasms; pregnancy; cancer epidemiology; orchiectomy; fertility; retroperitoneal space; male fertility; germinoma; infertility, male; pregnancy rate; humans; human; male; female; priority journal; article
Journal Title: Journal of Clinical Oncology
Volume: 16
Issue: 2
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 1998-02-01
Start Page: 733
End Page: 734
Language: English
PUBMED: 9469364
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 12 December 2016 -- Source: Scopus
Citation Impact
MSK Authors
  1. Pramod C Sogani
    75 Sogani
  2. Harry W Herr
    594 Herr