12 Results

People

  1. Li
    Li
  2. Crump
    Crump
  3. Gestsik
    Gestsik
  4. Tarassishin
    Tarassishin
  5. Ahn
    Ahn
  6. Baker
    Baker
  7. Bassit
    Bassit
  8. Castro
    Castro
  9. Chau
    Chau
  10. Chiu
    Chiu

Groups

  1. GSK Faculty (10)
  2. Molecular Pharmacology and Chemistry Program Faculty (10)
  3. Population Sciences Research Program (10)
  4. Sloan Kettering Institute Faculty (10)
  5. Sloan Kettering Institute Postdocs (1)
  1. "presenilin"
Formats
  1. Journal Article (12)
Groups
  1. GSK Faculty (10)
  2. Molecular Pharmacology and Chemistry Program Faculty (10)
  3. Population Sciences Research Program (10)
  4. Sloan Kettering Institute Faculty (10)
  5. Sloan Kettering Institute Postdocs (1)
People
  1. Yueming Li (10)
  2. Christina Crump (3)
  3. Leonid Tarassishin (3)
  4. Natalya Gestsik (3)
  5. Kwangwook Ahn (2)
  6. Bhramdeo Bassit (1)

More People

Years
  1. 2016 (2)
  2. 2015 (2)
  3. 2012 (1)
  4. 2011 (3)
  5. 2009 (1)
  6. 2007 (1)

More Years

Publications
  1. Proceedings of the National Academy of Sciences of the United States of America (3)
  2. ACS Chemical Neuroscience (2)
  3. Brain Research (1)
  4. EMBO Journal (1)
  5. Frontiers in Aging Neuroscience (1)
  6. Journal of Biological Chemistry (1)

More Publications

Publishers
  1. National Academy of Sciences (3)
  2. American Chemical Society (2)
  3. American Society for Biochemistry and Molecular Biology (1)
  4. Elsevier Inc. (1)
  5. Elsevier Science, Inc. (1)
  6. Frontiers Research Foundation (1)

More Publishers

Results (12)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • Development of sulfonamide photoaffinity inhibitors for probing cellular γ-secretase
    Journal Article

    Crump, C. J.; Murrey, H. E.; Ballard, T. E.; am Ende, C. W.; Wu, X.; Gertsik, N.; Johnson, D. S.; Li, Y. M.
    ACS Chemical Neuroscience (2016)

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  • Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
    Journal Article

    Paquet, D.; Kwart, D.; Chen, A.; Sproul, A.; Jacob, S.; Teo, S.; Olsen, K. M.; Gregg, A.; Noggle, S.; Tessier-Lavigne, M.
    Nature (2016)

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  • Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
    Journal Article

    Dang, S.; Wu, S.; Wang, J.; Li, H.; Huang, M.; He, W.; Li, Y. M.; Wong, C. C. L.; Shi, Y.
    Proceedings of the National Academy of Sciences of the United States of America (2015)

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  • Complex regulation of γ-secretase: From obligatory to modulatory subunits
    Journal Article

    Gertsik, N.; Chiu, D.; Li, Y. M.
    Frontiers in Aging Neuroscience (2015)

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  • Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies
    Journal Article

    Zhang, X. L.; Hoey, R. J.; Lin, G. Q.; Koide, A.; Leung, B.; Ahn, K.; Dolios, G.; Paduch, M.; Ikeuchi, T.; Wang, R.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2012)

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  • Piperidine acetic acid based γ-secretase modulators directly bind to presenilin-1
    Journal Article

    Crump, C. J.; Fish, B. A.; Castro, S. V.; Chau, D. M.; Gestsik, N.; Ahn, K.; Stiff, C.; Pozdnyakov, N.; Bales, K. R.; Johnson, D. S.; more...
    ACS Chemical Neuroscience (2011)

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  • Target of γ-secretase modulators, presenilin marks the spot
    Journal Article

    Crump, C. J.; Johnson, D. S.; Li, Y. M.
    EMBO Journal (2011)

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  • Mitochondrial protein quality control during biogenesis and aging
    Journal Article

    Baker, B. M.; Haynes, C. M.
    Trends in Biochemical Sciences (2011)

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  • Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 γ-secretase complexes
    Journal Article

    Placanica, L.; Tarassishin, L.; Yang, G.; Peethumnongsin, E.; Kim, S. H.; Zheng, H.; Sisodia, S. S.; Li, Y. M.
    Journal of Biological Chemistry (2009)

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  • [3H]-L-685,458 as a radiotracer that maps γ-secretase complex in the rat brain: Relevance to Aβ genesis and presence of active presenilin-1 components
    Journal Article

    Xiong, K.; Clough, R. W.; Luo, X. G.; Struble, R. G.; Li, Y. M.; Yan, X. X.
    Brain Research (2007)

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