Synapse - American Association for Cancer Research

Results (32)

MEK inhibitors lead to PDGFR pathway upregulation and sensitize tumors to RAF dimer inhibitors in NF1-deficient malignant peripheral nerve sheath tumor

Journal Article

Miranda-Román, M. A.; Lee, C. J.; Fishinevich, E.; Ran, L.; Patel, A. J.; Yan, J.; Khudoynazarova, M. N.; Warda, S.; Pachai, M. R.; Chen, Y.; more...
Clinical Cancer Research (2024)

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Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series

Journal Article

Anselmino, N.; Labanca, E.; Shepherd, P. D. A.; Dong, J.; Yang, J.; Song, X.; Nandakumar, S.; Kundra, R.; Lee, C.; Schultz, N.; more...
Clinical Cancer Research (2024)

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Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert tumor microenvironment

Meeting Abstract

Yan, J.; Chen, Y.; Patel, A. J.; Lee, C. J.; Warda, S.; Nixon, B. G.; Wong, E. W. P.; Miranda-Román, M. A.; Yang, N.; Wang, Y.; more...
Cancer Research (2022)

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Inactivation mutations of KMT2C/D license a molecular "field effect" and prime the urothelium for tumorigenesis

Meeting Abstract

Wang, N.; Pachai, M. R.; Li, D.; Lee, C.; Warda, S.; Xie, G.; Qian, C.; Wong, W. P. E.; Yan, J.; Hu, W.; more...
Cancer Research (2022)

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Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets

Meeting Abstract

Tang, F.; Xu, D.; Wang, S.; Wong, C. K.; Martinez-Fundichely, A.; Lee, C.; Cohen, S.; Park, J.; Hill, C.; Eng, K.; more...
Cancer Research (2022)

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PRC2 inactivating mutations amplify cell death in response to DNMT1-targeted therapy through enhanced viral mimicry in malignant peripheral nerve sheath tumor

Meeting Abstract

Chi, P.; Patel, A. J.; Warda, S.; Maag, J. L. V.; Misra, R.; Miranda-Román, M. A.; Pachai, M. R.; Lee, C. J.; Li, D.; Wang, N.; more...
Clinical Cancer Research (2022)

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XL-ing at induction of apoptosis in kidney cancer through inhibition of BCL-X(L)

Editorial

Wang, N.; Hakimi, A. A.; Chen, Y.
Clinical Cancer Research (2022)

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Phase Ib trial of the combination of imatinib and binimetinib in patients with advanced gastrointestinal stromal tumors

Journal Article

Chi, P.; Qin, L.; Camacho, N.; Kelly, C. M.; D'Angelo, S. P.; Dickson, M. A.; Gounder, M. M.; Keohan, M. L.; Movva, S.; Nacev, B. A.; more...
Clinical Cancer Research (2022)

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Differences in prostate cancer genomes by self-reported race: Contributions of genetic ancestry, modifiable cancer risk factors, and clinical factors