Synapse - James C Lee

James C Lee

Research Focus

Former Employee. Medicine; Instructor

Recent additions – View all

CD19-targeted CAR T cells "armored" to secrete IL-12 demonstrate superior efficacy against B cell acute lymphoblastic leukemia and resist treg immunosuppression
Meeting Abstract

Chang, P. S.; Lee, J. C.; Koneru, M.; Brentjens, R. J.
Molecular Therapy (2015)

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Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
Journal Article

Pegram, H. J.; Lee, J. C.; Hayman, E. G.; Imperato, G. H.; Tedder, T. F.; Sadelain, M.; Brentjens, R. J.
Blood (2012)

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In vivo inhibition of human CD19-targeted effector T cells by natural T regulatory cells in a xenotransplant murine model of B cell malignancy
Journal Article

Lee, J. C.; Hayman, E.; Pegram, H. J.; Santos, E.; Heller, G.; Sadelain, M.; Brentjens, R.
Cancer Research (2011)

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Co-authors at MSK

6

Brentjens
5

Sadelain
2

Hayman
2

Pegram
2

Santos
1

Heller
1

Imperato
1

Koneru
1

La Perle
1

Larson
1

Nikhamin
1

Punzalan
1

Yeh

Types of Work

Publications