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Christopher C Shelton

Formats
  1. Journal Article (7)
  2. Meeting Abstract (5)
Groups
  1. GSK Faculty (10)
  2. Molecular Pharmacology and Chemistry Program Faculty (10)
  3. Population Sciences Research Program (10)
  4. Sloan Kettering Institute Faculty (10)
  5. Biostatistics Service (2)
  6. Colorectal Surgery (2)

More Groups

People
  1. Yueming Li (10)
  2. Gary Schwartz (6)
  3. Raymond Meng (6)
  4. Yuan Tian (3)
  5. Hakim Djaballah (2)
  6. Li-Xuan Qin (2)

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Years
  1. 2010 (1)
  2. 2009 (6)
  3. 2008 (2)
  4. 2007 (1)
  5. 2006 (1)
  6. 2005 (1)
Publications
  1. Cancer Research (5)
  2. Proceedings of the National Academy of Sciences of the United States of America (3)
  3. Assay and Drug Development Technologies (1)
  4. Bioorganic & Medicinal Chemistry Letters (1)
  5. Journal of Clinical Oncology (1)
  6. Molecular Neurodegeneration (1)
Publishers
  1. American Association for Cancer Research (5)
  2. National Academy of Sciences (3)
  3. American Society of Clinical Oncology (1)
  4. Biomed Central Ltd (1)
  5. Mary Ann Liebert, Inc (1)
  6. Pergamon-Elsevier Science Ltd (1)

Results (12)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • Activation and intrinsic γ-secretase activity of presenilin 1
    Journal Article

    Ahn, K.; Shelton, C. C.; Tian, Y.; Zhang, X.; Gilchrist, M. L.; Sisodia, S. S.; Li, Y. M.
    Proceedings of the National Academy of Sciences of the United States of America (2010)

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  • Suppression of notch signaling with gamma-secretase inhibitors sensitizes malignant peripheral nerve sheath tumors to inhibitors of the Ras/Raf and PI3K/Akt pathways
    Meeting Abstract

    Meng, R. D.; Shelton, C. C.; Li, Y.; Schwartz, G. K.
    Cancer Research (2009)

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  • Stereo-controlled synthesis of novel photoreactive γ-secretase inhibitors
    Journal Article

    Yang, G.; Yin, Y. I.; Chun, J.; Shelton, C. C.; Ouerfelli, O.; Li, Y. M.
    Bioorganic & Medicinal Chemistry Letters (2009)

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  • A miniaturized 1536-well format γ-secretase assay
    Journal Article

    Shelton, C. C.; Tian, Y.; Shum, D.; Radu, C.; Djaballah, H.; Li, Y. M.
    Assay and Drug Development Technologies (2009)

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  • Modulation of γ-secretase specificity using small molecule allosteric inhibitors
    Journal Article

    Shelton, C. C.; Zhu, L.; Chau, D.; Yang, L.; Wang, R.; Djaballah, H.; Zheng, H.; Li, Y. M.
    Proceedings of the National Academy of Sciences of the United States of America (2009)

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  • An exo-cell assay for examining real-time γ-secretase activity and inhibition
    Journal Article

    Shelton, C. C.; Tian, Y.; Frattini, M. G.; Li, Y. M.
    Molecular Neurodegeneration (2009)

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  • γ-secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity
    Journal Article

    Meng, R. D.; Shelton, C. C.; Li, Y. M.; Qin, L. X.; Notterman, D.; Paty, P. B.; Schwartz, G. K.
    Cancer Research (2009)

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  • Use of the Notch signaling pathway to predict disease progression and distant recurrence-free survival in early stage colon cancer
    Meeting Abstract

    Meng, R. D.; Qin, L.; Shelton, C. C.; Gerald, W. L.; Barany, F.; Notterman, D.; Li, Y.; Paty, P. B.; Schwartz, G. K.
    Journal of Clinical Oncology (2008)

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  • Dual inhibition of the Notch and Hedgehog developmental pathways in colon cancers suppresses viability by combined downregulation of the PI3K/Akt pathway
    Meeting Abstract

    Meng, R. D.; Shelton, C. C.; Li, Y. M.; Schwartz, G. K.
    Cancer Research (2008)

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  • Gamma-secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity
    Meeting Abstract

    Meng, R. D.; Shelton, C. C.; Cheema, H. S.; Li, Y.; Schwartz, G. K.
    Cancer Research (2007)

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